UEFA Champions League score predictions, picks for Tuesday, March 4: Real Madrid sneaks past Atletico Madrid

The UEFA Champions League Round of 16 begins on Tuesday with four star-studded showdowns. The first match of the day features Club Brugge hosting Aston Villa at 12:45 p.m. ET. These two teams squared off on Matchday 4, with Club Brugge securing a 1-0 win at home in November. Three more matches are set to follow at 3 p.m. ET, including a renewal of the Madrid Derby between Real Madrid and Atletico Madrid. Real Madrid are the -115 favorites (risk $115 to win $100) on the 90-minute money line, with Atletico Madrid the +320 underdogs. A draw is priced at +270, and the over/under for total goals is 2.5. You can catch every UEFA Champions League match on Paramount+. 

Paramount+ is the place to watch the Champions League this season. A subscription also gives you access to other sports content including the UEFA Europa League, Serie A, EFL League One, NFL on CBS, Big Ten on CBS, and countless movies and shows. You can now get a free 7-day trial, so sign up right here.  

SportsLine’s proven model has simulated every Tuesday UEFA Champions League game 10,000 times and revealed exact score predictions and best bets for every match. See all the UEFA Champions League score predictions and expert picks at SportsLine now. 

Club Brugge vs. Aston Villa, 12:45 p.m. ET

• How to watch Club Brugge vs. Aston Villa: Stream on Paramount+ (Get your first seven days free)
• Club Brugge vs. Aston Villa betting odds: Club Brugge +200, Draw +220, Aston Villa +145

Club Brugge vs. Aston Villa preview: Club Brugge advanced to the Round of 16 convincingly, knocking off Atalanta 5-2 on aggregate. Aston Villa, meanwhile, are coming off a 2-0 win over Cardiff City in the fifth round of the FA Cup on Friday. These two squared off in Champions League play in November, with Club Brugge securing a 1-0 win at home. Stream the game here and check out full soccer coverage on CBS Sports Golazo Network.

Club Brugge vs. Aston Villa score prediction: Club Brugge 3, Aston Villa 0

Bonus pick: Soccer expert Jon Eimer has locked in three best bets for this match, including two that offer plus-money payouts. See all of his Club Brugge vs. Aston Villa picks right here. 

Real Madrid vs. Atletico Madird, 3 p.m. ET

• How to watch Real Madrid vs. Atletico Madrid: Stream on Paramount+ (Get your first seven days free)
• Real Madrid vs. Atletico Madrid betting odds: Real Madrid -115, Draw +270, Atletico Madrid +320

Real Madrid vs. Atletico Madrid preview: These two foes are extremely familiar with each other. These rivals last squared off on Feb. 8 in La Liga play, which ended in a 1-1 draw. The past three meetings between these cross-town rivals have finished in a 1-1 stalemate. Stream the game here and check out full soccer coverage on CBS Sports Golazo Network.

Real Madrid vs. Atletico Madrid score prediction: Real Madrid 2, Atletico Madrid 1 

Want more picks? SportsLine’s soccer insider Brandt Sutton has analyzed the Real Madrid vs. Atletico Madrid match from every angle and locked in his best bet right here. 

PSV vs. Arsenal, 3 p.m. ET

• How to watch PSV vs. Arsenal: Stream on Paramount+ (Get your first seven days free)
• PSV vs. Arsenal betting odds: PSV +300, Draw +240, Arsenal -105

Arsenal vs. PSV preview: PSV advanced to the Round of 16 following a thrilling 3-1 win over Juventus on home soil that saw the Dutch side advance 4-3 on aggregate. Arsenal, meanwhile, limp into Tuesday’s contest winless in three of their last four matches overall. Stream the game here and check out full soccer coverage on CBS Sports Golazo Network.

PSV vs. Arsenal score prediction: PSV 1, Arsenal 1

Even more picks: European soccer expert Martin Green has locked in two picks for PSV vs. Arsenal, including one that pays more than +200. Get his best bets right here. 

Borussia Dortmund vs. Lille, 3 p.m. ET

• How to watch Borussia Dortmund vs. Lille: Stream on Paramount+ (Get your first seven days free)
• Borussia Dortmund vs. Lille betting odds: Borussia Dortmund -170, Draw +310, Lille +470

Borussia Dortmund vs. Lille preview: Borussia Dortmund are unbeaten in their last three games across all competitions, outscoring their opposition 8-0 during that span. Lille, meanwhile, are coming off a 4-1 loss at PSG over the weekend. However, Lille have won three of their past four matches in this competition, which includes a dominant 6-1 win over Feyenoord in their last UCL appearance. Stream the game here and check out full soccer coverage on CBS Sports Golazo Network.

Borussia Dortmund vs. Lille score prediction: Borussia Dortmund 1, Lille 1

Bonus pick: SportsLine’s Matt Severance, who’s 7-2 (+517) over his last nine Champions League picks, has locked in his best bet for Dortmund vs. Lille right here. 

Where to bet on UEFA Champions League games

Here are some of the sportsbooks to bet on Champions League games today, along with the various UEFA Champions League sportsbook promos they currently offer.